CLONS is complex and multi-disciplinary project and we have organized a set of sub-projects to group together dependant partners and minimize integration confounds. 
CLONS pert diagram

Sub-Project 0: Management, dissemination, and exploitation

  • WP1 – Project Management
  • WP10 – Dissemination and exploitation

Sub-Project 1: Implantable Components

  • WP2 – Implantable interfaces
  • WP3 – Electronic circuitries

Sub-Project 2: External Components

  • WP4 – Wearable system for inertial sensing
  • WP5 – Decoding, encoding, and learning algorithms
  • WP6 – System integration, user training, and assessment infrastructure

Sub-Project 3: Neuroscientific and clinical experiments

  • WP7 – Neuroscientific models
  • WP8 – In-vivo experiments in animals
  • WP9 – In-vivo experiments in human subjects

 Project activities will be divided into three different phases (partly overlapped): CLONS work phases

PHASE 1:

Preliminary in-vivo experiments will be carried out using existing systems and algorithms already available in the Consortium. This is possible thanks to the important previous experiences of the partners. For example, Fraunhofer-IBMT has already developed bidirectional interfaces for neuroprosthesis. The neurophysiological, neuroscientific, and clinical partners (CNRS-LPPA, UG, MEEI) have already carried out similar experiments in the past. For example, CNRS-LPPA has experience in modelling the vestibular system (Laurens and Droulez, 2008) and will responsible of these activities in the project. MEEI and UG in carrying out experiments in animal and human models. It will allow the technological partners to gather important information to develop more effective systems. This is a significant advantage due to the high-quality and experienced Consortium characterizing the CLONS proposal.

PHASE 2:

The technological partners will develop new systems and algorithms to be used for the implementation of the vestibular neural prosthesis This phase is very important in order to design and implement new solutions able to overcome the limits of current solutions.

PHASE 3:

The vestibular neural prosthesis will be tested in different models. Particular attention will be devoted to the analysis of the assessment of the performance of the user in combination with the vestibular neural prosthesis. Phases 1 and 2 will go almost in parallel during the first half of the project. Phase 3 will be carried out during the second half of the project (see Figure 3). It is important to point out that as in every integrated project the research activities will never stop. In-vivo experiments will go on also during Phase 2 even if the emphasis will be more on the technological developments (and vice versa for Phase 3). The goals of a challenging project as CLONS can be achieved only thanks to the continuous efforts of all the partners. The Demonstrator of the CLONS Project will be developed by integrating (WP6) the following modules: (1) implantable interfaces (WP2); (2) implantable electronics (WP3); (3) wearable system (WP4); (4) encoding (Task 5.2) and learning (Task 5.3) algorithms (WP5).